What is Cord Blood?
Cord blood is the blood that circulates from the baby to the placenta through the umbilical cord. It is a rich source of hematopoietic stem cells, which is believed to have the ability to treat blood-related cancers, immune system and genetic disorders. Therefore, cord blood can potentially save lives via hematopoietic stem cells transplantation.
Cord Blood Donation
Cord blood is collected after the baby is delivered and its umbilical cord is cut.
The donated cord blood is processed and kept at the National Blood Centre. In order to ensure the safety and health of the patients who received this transplant, only cord blood that meets the criteria and of highest quality will be processed and stored.
The eligibility for donating cord blood is as follows:
- Mother of 18 years old and above.
- Married and not a single parent.
- Malaysian citizen.
- Period of gestation is 36 weeks and above.
- Parents are not HIV positive.
- Mother is not Hepatitis B or C carrier.
- Mother is not a sex worker.
- Mother does not have a sexual relationship with a homosexual.
- Mother does not have a sexual relationship with hemophilic patients who previously received factor concentrates as treatment.
- Parents do not have chronic disease.
- Parents do not have history of genetic disease.
Procedure of Cord Blood Donation
- Interested couples can get information of the cord blood donation
- from the webpage of National Blood Centre (pdn.gov.my),
- contact the National Cord Blood Bank at National Blood Centre, Jalan Tun Razak, 50400 Kuala Lumpur or call 03-266933888, or.
- contact the cord blood collection centres at the Department of Obstetrics and Gynaecology at Hospital Kuala Lumpur, Hospital Selayang, Hospital Serdang and Hospital Ampang.
- A medical doctor or nurse will be conducting an interview with the donor to ensure that the eligibility is met. Details of the family medical history, lifestyle and sexual history will be taken during the interview.
- The eligible mother is required to complete the informed consent form and questionnaires regarding her health status. Counseling sessions for parents will also take place so that they understand the donation process clearly. The informed consent form must be brought along by the donor during admission to the Labour Room.
- Maternal blood samples are taken for the purpose of infectious diseases screening. This process is important to make sure the donated cord blood units are free from any potential infectious disease.
- The collection of umbilical cord blood will be carried out after the baby is safely delivered and while waiting for the placenta to be expelled. Cord blood collection procedure is safe, painless and does not harm the baby and mother.
- The collected cord blood and maternal samples will be transported to the Cord Blood Processing Laboratory at the National Blood Centre. The blood samples are due for testing, processing and cryopreservation.
Processing and Cryopreservation of Cord Blood Unit
Transportation of cord blood unit and maternal samples from the cord blood collection centres to the National Blood Centre are done in controlled temperature to ensure the viability and integrity of the blood. Cord blood units are processed under sterile condition and later preserved at the temperature of -196°C within 48 hours from the time of collection.
- Firstly, the collected cord blood units and the maternal samples are subjected to physical examination. Laboratory technologist will verify the accuracy of the details in the informed consent form and the blood samples.
Infectious diseases may be transmitted through body fluids from mother to baby during pregnancy. Therefore, Blood samples will be tested for pathogens (agents that cause diseases) such as Hepatitis, Cytomegalovirus (CMV), Human Immunodeficiency Virus (HIV) (causes AIDS) and syphilis. All information of the donors and test results are strictly confidential.
If one of the above screening tests showed positive reactions, the donor shall be notified. Donor shall be duly counselled and her blood samples will be taken for confirmation testing. This is mandatory under the Communicable Diseases Prevention and Control Act 1988.
Searching for a Matching Cord Blood Unit
When a patient is in need of a transplant for a life-threatening disease, the doctor will forward request for finding a matched cord blood to Cord Blood Division at the National Blood Centre.
|Last Reviewed||:||31 January 2016|
|Writer||:||Lina Wati bt. Durani|
|Accreditor||:||Katheleen Ng Li Fong|